Oct 01, 2014 objectives caralluma is a xerophytic genus used as traditional medicine for the treatment of diabetes, inflammation, leprosy, obesity and rheumatism. Acylated pregnane glycosides from caralluma quadrangula. Full text effects of caralluma russeliana stem extract on. Monolluma is a genus of plants in the apocynaceae, first described as a genus in 1995. Russelioside b rb is a pregnane glycoside obtained from caralluma quadrangula. Russelioside b from caralluma quadrangula improved hepatic glucose metabolism in diabetic rats. The first extract is produced by optionally pretreatment of plant materials, optional crushing andor grinding, extraction, and concentration. Monolluma cicatricosa deflers plowes, synonym of caralluma cicatricosa deflers n. Antidiabetic effect of monolluma quadrangula is mediated via.
The present study aimed to investigate the effect of m. Monolluma quadrangula protects against oxidative stress. The aim of this study was to investigate the effects of caralluma russeliana stem extract on some physiological parameters in. An monolluma quadrangula in nahilalakip ha genus nga monolluma, ngan familia nga apocynaceae. Pdf pharmacological action of a pregnane glycoside. Caralluma uhlig kakteen more than 5,000 different species. Abdelsattar et al evaluated the antihyperglycemic effects of c. Pdf antihyperglycemic activity of caralluma quadrangula. Aug 09, 2000 the aerial parts of caralluma russeliana yielded four new pregnane glycosides, russeliosides a. E br asclepiadaceae is cactuslike in shape with smooth, light green and quadrangular stems with a coarsely crenate to undulate. The genus caralluma includes around 100 variable species of stem succulents with clumps of angular fleshy stems, often bearing prominent pointed tubercles vestigal leaves.
It might be expected to be a challenge to look at the saudi plants in order to discover new sources for new molecules which may have anticancer activity. Caralluma russeliana, diabetes, streptozotocin, weight. Antimicrobial activity of caralluma quadrangula forssk n. Sep 28, 2011 many natural products from plants have been identified to exert anticancer activity.
Asclepiadaceae h endemic 76 cardiospermum canescens wall. Antidiabetic effect of monolluma quadrangula is mediated. In a previous study, the methanolic extract as well as the chloroform fraction of the aerial parts of caralluma quadrangula. Caralluma quadrangula oman uhlig kakteen more than 5,000. Therapeutic potential of russelioside b as antiarthritic. Studies complementary and alternative medicine, pharmacognosy, and plant biology. Abstract caralluma fimbriata extract has received generally. Ann caralluma quadrangula forssk ne br latex from res rev biol 2014. Pdf caralluma is one of the prominent genus out of 200 genera and. Pregnane glycosides from caralluma russeliana journal of.
Six species of caralluma have been found to occur in oman. In this research, alcoholic extract from caralluma arabica and different solvent fractions were evaluated for their antioxidant, antiinflammatory and anticancer properties as well as their polyphenolic compositions. India, africa, saudi arabia, the middle east, and pakistan. Aasblumen uhlig kakteen more than 5,000 different species. Research article monolluma quadrangula protects against. Full text effects of caralluma russeliana stem extract on some.
The gastroprotective effects of hydroalcoholic extract of. Forman menispermaceae cl common urikka kodi 98 cissus quadrangula l. Caralluma species are traditional edible herbs used in folkloric medicine as antidiabetic, antioxidant, antipyretic, antirheumatic, antiinflammatory and anthelmintic agents. Phytochemicals have been of great interest as a source of natural antioxidants used for health promotion, food preservation, food flavoring and cosmetics. For delivery time to other countries and details on the calculation of the delivery date, please see shipping charges, returns, delivery time. Caralluma tuberculata and caralluma edulis are the 2 species of the genus that are grown in pakistan. Binjumah, monolluma quadrangula protects against oxidative stress and modulates ldl receptor and fatty acid synthase gene expression in hypercholesterolemic rats, oxidative medicine and cellular longevity, 10. In a previous study, the methanolic extract as well as the chloroform fraction of the aerial parts of caralluma quadrangula forssk. The current study was designed to explore the antidiabetic potential of. Asclepiadaceae h common muyalkombuchedi 75 caralluma diffusa wight n. Request pdf acylated pregnane glycosides from caralluma quadrangula in a previous study, the methanolic extract as well as the chloroform fraction of the aerial parts of caralluma quadrangula. Monolluma quadrangula 1 ar en oleandervaxtart som forst beskrevs av peter forsskal, och fick sitt nu gallande namn av d. Antioxidant activity and lipoxygenase inhibitory effect of.
New pregnane glycosides from caralluma tuberculata journal. The present study has examined the alcoholic extract of caralluma quadrangula ca qu for its quantitative and qualitative composition and its antioxidant as well as antihemolytic properties. In the first caralluma extract, the resinous material does not exceed 0. Effect of aqueous fraction of caralluma tuberculata on blood glucose and body weightthe effect of aqueous fraction of caralluma tuberculata on blood glucose in alloxaninduced diabetic rabbit is presented in table 1. Diabetes of type 2 is a worldwide epidemic disease of global prevalence. Caralluma quadrangula the source of russeliosid b has been used by bedouins of saudi communities in cases of thirst and hunger and for the treatment of diabetes, vitiligo, melasma and freckles. Dec 01, 2017 in a continuation of our interest in the chemical and biological investigation of the members of genus caralluma, the antihyperglycemic activity of the extracts, fractions and the major pregnane glycoside of the aerial parts of c. The methanolic extracts of forty species of plants traditionally used in saudi arabia for the treatment of a variety of diseases were tested in vitro for. Antihyperglycemic activity of caralluma quadrangula in. Caralluma stems may be recumbent or erect with considerable variation in diameter 0. Jun 12, 2020 caralluma tuberculata is a cooked food item in pakistan especially for diabetics. The present experiment tested the possible role of rb in controlling weight gain in rats fed on high fat hf diet. Compounds 1, 2 and 4 showed promising cytotoxic activity against mcf7 cell line. The findings have potential implications for plausible intervention in.
Antihemolytic activity and antioxidant studies of caralluma. Caralluma quadrangula is wild saudi plant used by traditional healers as antidiabetic, in case of hunger, and many other. Introduction throughout human civilizations, plants and their derivatives have been used in traditional medicine for the therapeutic management of several diseases and thus have affected human health for. Caralluma quadrangula, antioxidant, antihemolytic, nutraceutical. Caralluma quadrangula, caralluma tuberculata, hibiscus shizopetalous, hibiscus subdariffa white variety and. Pdf phytodiversity in the madukkarai hills of south. New pregnane glycosides from caralluma tuberculata. Bulletin of faculty of pharmacy, cairo university 2017, 55 2, 269272. Download pdf download all download jpeg 2000 download text. Introduction throughout human civilizations, plants and their derivatives have been used in traditional medicine for the therapeutic management of several diseases and thus have affected human health for centuries. Caralluma quadrangula oman uhlig kakteen more than.
The present study was aimed to evaluate the improving effect of russelioside b rb, a. The structure of isolated compounds were elucidated by nmr and hresims analysis. It has quadrangular stems and forms large clumps up to 1520. New pregnane glycosides from caralluma hexagona lavranos. Research article antihemolytic activity and antioxidant studies of. Antihemolytic activity and antioxidant studies of caralluma quadrangula. Full text effects of caralluma russeliana stem extract. Effects of caralluma russeliana stem extract on some physiological parameters in streptozotocininduced diabetic male rats talal a zari, mesfer a althebaiti department of biological sciences, faculty of science, king abdulaziz university, jeddah, saudi arabia purpose. Monolluma quadrangula ingar i slaktet monolluma och familjen oleandervaxter.
Abdelsattaracylated pregnane glycosides from caralluma quadrangula phytochemistry, 88 20, pp. Caralluma quadrangula is wild saudi plant used by traditional healers as antidiabetic, in case of hunger, and. Monolluma quadrangula protects against oxidative stress and. The fresh plant is eaten to treat gastric ulcers and diabetes and is also used as appetite suppressant. A little is known about the antibacterial activity of caralluma extracts of stem and roots of caralluma quadrangula, regarding its latex, not much information available. The findings have potential implications for plausible intervention in reactive oxygen species ros mediated pathologies. A caralluma extract and a method of making thereof which can be standardized and reproducible, and which prevents the glycosides from decomposition, which can reduce the undesirable nonglycoside components. International association for plant taxonomy iapt stable url. Therefore, we carried out this investigation to study the antihypercholesterolemic e. Us7060308b2 caralluma extract products and processes for. Rb was separated from the nbutanol fraction of the crude methanolic extract by.
Ammar bader, umm alqura university, makkah, saudi arabia, pharmacognosy department, faculty member. Pdf antihyperglycemic activity of caralluma umbellata haw. Antihyperglycemic activity of caralluma tuberculata in. Ammar bader umm alqura university, makkah, saudi arabia. We found many specimens of euphorbia balsamifera subsp. Caralluma quadrangula antimicrobial 75 antidiabetic 118 caralluma negevensis anticancer. An monolluma quadrangula in uska species han magnoliopsida nga syahan ginhulagway ni peter forsskal, ngan ginhatag han pagkayana nga asya nga ngaran ni d.
Five new steroidal glycosides from caralluma dalzielii. Essential oil composition of stems and fruits of caralluma europaea n. Frontiers pharmacological action of a pregnane glycoside. In a continuation of our interest in the chemical and biological investigation of the members of genus caralluma, the antihyperglycemic activity of the extracts, fractions and the major pregnane glycoside of the aerial parts of c. Several caralluma species showed antihyperglycemic activity of their crude extracts or. Monolluma quadrangula is a succulent bush traditionally used to treat diabetes and peptic ulcer. Also seeds, substrates, fertilizers, accessories and much more. Caralluma quadrangula is wild saudi plant used by traditional healers as antidiabetic. New pregnane glycosides from caralluma hexagona lavranos and. Article views are the countercompliant sum of full text article downloads since november 2008 both pdf and html across all institutions and individuals. It contains only one known species, monolluma quadrangula, native to middle east.
Pdf caralluma quadrangula extract is widely used by different ethnic group of the world for a long time for the treatment of diseases. The scheme to hypothesize that phytoconstituents of caralluma quadrangula extract are bioeffective antioxidants. Pdf antihyperglycemic activity of caralluma quadrangula in. Hypercholesterolemia is a metabolic disorder associated with oxidative stress. Plant authentication was done by a staff member at the taxonomy department at the faculty of science in king abdulaziz university and a specimen cq 1027b was deposited in. Antihyperglycemic activity of caralluma quadrangula in streptozotocininduced diabetic rats. In addition, the study evaluated the antioxidant and anti. A succulent perennial, erect sparselybranched to 40 cm high, with quadrangular branches, of dry sahel locations in senegal to nw nigeria, and also in the. In vitro cytotoxic screening of selected saudi medicinal. Download fullsize image highlights four acylated pregnane glycosides were isolated from caralluma quadrangula. Potential for nutraceutical development in cancers and blood disorders.
It is known as caralluma quadrangula and has been used in folk medicine for the treatment of dm and. Check pages 1 7 of new dietary ingredient notification. Pdf phytochemical library of caralluma genus researchgate. Russelioside b from caralluma quadrangula improved hepatic. This study was conducted on caralluma tuberculata, a famous traditional medicinal plant in the northern territory of. The present study investigated the protective effect of monolluma quadrangula extract on hypercholesterolemiainduced oxidative stress in the liver and heart of highcholesteroldiet hcd fed rats. Although the entire plant of caralluma quadrangula is edible, in some. Download hires image download to mspowerpoint cite this.
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